Kinetic models settings
Calculation settings
| Name | Type | Description |
|---|---|---|
Multiple substances analysis
|
Boolean |
Specifies whether the assessment involves multiple substances. |
Include dietary and non-dietary routes of exposure
|
Boolean |
Specifies whether the assessment involves both dietary and non-dietary (oral, inhalatory or dermal) routes of exposure. |
Restrict active substances to substances with available hazard characterisations
|
Boolean |
Restrict assessment group membership based on presence/absence of hazard characterisations. |
Default oral absorption factor for non-dietary exposure
|
Numeric |
When there is no kinetic model and absorption factors are not specified in file, non-dietary oral exposures (external doses) are multiplied by this factor to determine the absorbed (internal) dose. |
Default oral absorption factor for dietary exposure
|
Numeric |
When there is no kinetic model and absorption factors are not specified in file, dietary exposures (external doses) are multiplied by this factor to determine the absorbed (internal) dose . |
Default dermal absorption factor for non-dietary exposure
|
Numeric |
When there is no kinetic model and absorption factors are not specified in file, dermal exposures (external doses) are multiplied by this factor to determine the absorbed (internal) dose. |
Default inhalation absorption factor for non-dietary exposure
|
Numeric |
When there is no kinetic model and absorption factors are not specified in file, inhalation exposures (external doses) are multiplied by this factor to determine the absorbed (internal) dose. |
Number of days
|
Numeric |
The number of days. |
Number of events per day for the ORAL dietary dose
|
Numeric |
The daily dose is administered in equal portions (dose / number of events) per event. |
Number of initial days skipped
|
Numeric |
This period is skipped in the calculation of the mean internal exposure. |
Kinetic model
|
AlphaNumeric |
Code Kinetic Model. |
Use parameter variability
|
Boolean |
When specified, use parameter variability. |
Specify the type of kinetic model
|
InternalModelType | Specify the type of model to convert external exposure to the internal level. |
Number of events per day for the DERMAL nondietary dose
|
Numeric |
The daily dose is administered in equal portions (dose / number of events) per event. |
Number of events per day for the INHALATION nondietary dose
|
Numeric |
The daily dose is administered in equal portions (dose / number of events) per event. |
Number of events per day for the ORAL nondietary dose
|
Numeric |
The daily dose is administered in equal portions (dose / number of events) per event. |
Specify the hours (events).
|
Numeric |
Specify the hours (events) on which a dose is applied. Allowed numbers are 1, 2, 3, 4,…, 24 separated by spaces. |
Specify events
|
Boolean |
if checked, a sequence of hours can be specified, otherswise the events are derived based on the number of doses per day. |
Use kinetic conversion factors subgroup
|
Boolean |
Kinetic conversion factors are dependent on subgroups (e.g. based on age or gender, see dataformats KineticConversionfactorsSgs). |
Uncertainty settings
| Name | Type | Description |
|---|---|---|
Resample kinetic model parameter values
|
Boolean |
Specifies whether kinetic model parameter values are resampled. |