Exposure biomarker conversions data formats
Describes the exposure biomarker conversions (i.c. conversions within a biological matrix).
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Exposure biomarker conversions
Exposure biomarker conversions main table. Biomarker conversion is within a biological matrix.
Accepted table names: ExposureBiomarkerConversions, ExposureBiomarkerConversion, BiomarkerConversions, BiomarkerConversion.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idExposureBiomarkerConversion |
AlphaNumeric (50) |
Id of the exposure biomarker conversion |
idExposureBiomarkerConversion, idExposureBiomarkerFactor, idEBCFactor |
Yes |
idSubstanceFrom |
AlphaNumeric (50) |
Identification code of substance of the ‘from’ substance. That is, the code of the (measured) substance for which concentrations need to be translated. |
idSubstanceFrom, SubstanceIdFrom, SubstanceCodeFrom, SubstanceFrom |
Yes |
Biological matrix |
BiologicalMatrix | The biological matrix (e.g., blood, urine) for which this conversion rule is defined. |
BiologicalMatrix, MatrixSource, SourceMatrix |
Yes |
ExpressionTypeFrom |
ExpressionType | The expression type (or adjustment method) of the ‘from’-part. This field specifies how the dose unit (source) is expressed, e.g., for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’). |
ExpressionTypeFrom, AdjustmentMethodFrom |
No |
UnitFrom |
DoseUnit | The unit of the ‘from’-part of the conversion rule. |
UnitSourceFrom, SourceUnitFrom |
Yes |
idSubstanceTo |
AlphaNumeric (50) |
Identification code of substance of the ‘to’ substance. |
idSubstanceTo, SubstanceIdTo, SubstanceCodeTo, SubstanceTo |
Yes |
ExpressionTypeTo |
ExpressionType | TODO: to be removed. The expression type or adjustment method of ‘to’-part of the conversion rule. This field specifies how the dose unit (target) is adjusted, e.g., for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’). |
ExpressionTypeTo, AdjustmentMethodTo |
No |
UnitTo |
DoseUnit | TODO: to be removed. The unit of the ‘to’-part of the conversion rule. |
UnitSourceTo, SourceUnitTo |
Yes |
ConversionFactor |
Numeric |
The conversion factor value. If the conversion is provided as a distribution, then this factor is the nominal value of the distribution. |
ConversionFactor, Factor |
Yes |
VariabilityDistributionType |
BiomarkerConversionDistribution | Distribution type (Uniform, LogNormal or Beta). If not specified, the conversion is assumed to be a constant factor. |
VariabilityDistributionType, VariabilityDistribution, DistributionType, Distribution |
No |
VariabilityUpper |
Numeric |
The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is lognormal, then the upper value is assumed to correspond with the p95 percentile of the distribution. If the distribution is beta, then the upper value is the variance. For the uniform and lognormal distribution, this value should be greater than the conversion factor. For the beta distribution, it is restricted by the value of the conversion factor (the mean). |
VariabilityUpper, Upper |
No |
Exposure biomarker conversion subgroups
Exposure biomarker conversion subgroups.
Accepted table names: ExposureBiomarkerConversionSGs, BiomarkerConversionSGs, ExposureBiomarkerSGs, EBCFactorSubGroups.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idExposureBiomarkerConversion |
AlphaNumeric (50) |
Id of the exposure biomarker conversion |
idExposureBiomarkerConversion, idExposureBiomarkerFactor, idEBCFactor |
Yes |
ConversionFactor |
Numeric |
Conversion factor value |
ConversionFactor, Factor |
Yes |
AgeLower |
Numeric (50) |
Specifies the lower bound of the age interval (in years) of the exposure biomarker conversion subgroup. Individuals belong to a subgroup when the age of the individual is equal or greater than the specified lower bound and smaller than the specified lower age of the next subgroup. |
AgeLower, LowerAge |
No |
Gender |
GenderType | The gender of the exposure biomarker conversion subgroup. |
Gender, Sex |
No |
VariabilityUpper |
Numeric |
The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is log-normal, then the upper value is assumed to correspond with the p95 percentile of the distribution. When a distribution is assumed, this value should be greater than the conversion factor. |
VariabilityUpper, Upper |
No |