PBK models

External exposure can be from one or more exposure routes: oral (dietary or non-dietary), dermal or inhalation. Internal exposures are related to a specific compartment, (biological matrix), in a kinetic model.

Use one of the implemented kinetic models, with instances for specific substances defined in data table kinetic model instances and model parameters specified in data table kinetic model instance parameters.

Given a PBK model the calculation will fall back to a lower tier, see kinetic conversion factors module, in case of missing data.

This module has as primary entities: Substances

Output of this module is used by: Internal exposures Hazard characterisations

PBK models as data

Specify nondietary absorption factors as data.

Inputs used: Active substances

Settings used

Settings and Tiers