Kinetic conversion factors data formats

Data tables:
  • Kinetic conversion factors

Kinetic conversion factors convert external exposures from one or more external routes (dietary, non-dietary oral, dermal, inhalation) to an internal (target) compartment.

Kinetic conversion data format

The kinetic conversion factor data format.

Download empty dataset template: Zipped CSV Excel

Kinetic conversion factors

Kinetic conversion factors translating external (daily) exposures for specific routes to the resulting internal target intakes.

Accepted table names: KineticConversionFactors, KineticConversionFactor.

Table 328 Table definition for Kinetic conversion factors.
Name Type Description Aliases Required

idKineticConversionFactor

AlphaNumeric (50)

Id of the kinetic conversion factor

idKineticConversionFactor, idConversionFactor, idKCFactor

Yes

idSubstanceFrom

AlphaNumeric (50)

Code of substance (must correspond to values in id column of Substances table)

idSubstanceFrom, SubstanceIdFrom, SubstanceCodeFrom, SubstanceFrom

Yes

ExposureRouteFrom

ExposureRoute

The exposure route (only applicable if target level is external). If not specified, Dietary is assumed.

ExposureRoute

No

Biological matrix from

BiologicalMatrix

If applicable, the source matrix of the human body (e.g., blood, urine) to convert from. When specified, the measurements are considered at the level of internal doses.

MatrixSource, SourceMatrix

No

DoseUnitFrom

DoseUnit

The unit of the substance dose to convert from.

UnitSource, SourceUnit

Yes

ExpressionTypeFrom

ExpressionType

The expression type or adjustment method of the dose unit (from). This field specifies how the dose unit (source) is adjusted, e.g. for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’).

ExpressionTypeFrom, AdjustmentMethodFrom

No

idSubstanceTo

AlphaNumeric (50)

Code of substance (must correspond to values in id column of Substances table)

idSubstanceTo, SubstanceIdTo, SubstanceCodeTo, SubstanceTo

Yes

ExposureRouteTo

ExposureRoute

The exposure route (only applicable if target level is external) to convert to. If not specified, Dietary is assumed.

ExposureRoute

No

Biological matrix to

BiologicalMatrix

If applicable, the matrix of the human body (e.g., blood, urine) to convert to. When specified, the measurements are considered at the level of internal doses.

MatrixTarget, TargetMatrix

No

DoseUnitTo

DoseUnit

The unit of the substance dose to convert to.

UnitTarget, TargetUnit

Yes

ExpressionTypeTo

ExpressionType

The expression type or adjustment method of the dose unit (to). This field specifies how the dose unit (target) is adjusted, e.g. for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’).

ExpressionTypeTo, AdjustmentMethodTo

No

ConversionFactor

Numeric

Conversion factor value

ConversionFactor, Factor

Yes

UncertaintyDistributionType

KineticConversionFactorDistributionType

Distribution type (Uniform, LogNormal, Beta or InverseUniform). If not specified, the conversion is assumed to be a constant factor.

UncertaintyDistributionType, UncertaintyDistribution, DistributionType, Distribution

No

UncertaintyUpper

Numeric

The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is log-normal, then the upper value is assumed to correspond with the p95 percentile of the distribution. When a distribution is assumed, this value should be greater than the conversion factor.

UncertaintyUpper, Upper

No

Kinetic conversion factor subgroups

Kinetic conversion factor subgroups.

Accepted table names: KineticConversionFactorSGs, KCFactorSubGroups.

Table 329 Table definition for Kinetic conversion factor subgroups.
Name Type Description Aliases Required

idKineticConversionFactor

AlphaNumeric (50)

Id of the kinetic conversion factor

idKineticConversionFactor, idConversionFactor, idKCFactor

Yes

ConversionFactor

Numeric

Conversion factor value

ConversionFactor, Factor

Yes

AgeLower

Numeric (50)

Specifies the lower bound of the age interval (in years) of the kinetic conversion factor subgroup. Individuals belong to a subgroup when the age of the individual is equal or greater than the specified lower bound and smaller than the specified lower age of the next subgroup.

AgeLower, LowerAge

No

Gender

GenderType

The gender of the kinetic conversion factor subgroup.

Gender, Sex

No

UncertaintyUpper

Numeric

The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is log-normal, then the upper value is assumed to correspond with the p95 percentile of the distribution. When a distribution is assumed, this value should be greater than the conversion factor.

UncertaintyUpper, Upper

No