Risks

Risks (health impacts) are quantified by comparing exposures and hazard characterisations at the chosen level (external or internal) via margins of exposure (MOE) or more generalised or integrated margins of exposure (IMOE). In addition, risks can be assessed from a plot of hazard characterisations vs. exposures.

This module has as primary entities: Substances Effects Populations

Output of this module is used by: Single value risks

Calculation of risks

Risks (health impacts) are quantified by comparing exposures and hazard characterisations at the chosen level (external or internal) via margins of exposure (MOE) or more generalised or integrated margins of exposure (IMOE).

• Risks calculation

Inputs used: Exposures Hazard characterisations

Settings used

• Calculation Settings

Risks are expressed as (individual) margins of exposure and as a probability to exceed a reference value (e.g. 1 or 100), comparing the exposures and the hazard characterisation for individuals or individual-days in a population. Exposures, hazard characterisations and risks can be acute or chronic. The default unit for exposures and hazard characterisations is \(\mu g/kgBW/day\), but this can be changed by choosing non-default units for consumptions, concentrations and/or body weight.

The basic calculation is a graphical representation of hazard characterisations versus exposures.