Risks settings

Calculation settings

Table 197 Calculation settings for module Risks.

Name	Description
Multiple substances analysis	Specifies whether the assessment involves multiple substances.
Express results in terms of reference substance equivalents (cumulative)	Specifies whether the assessment involves multiple substances and results should be cumulated over all substances.
Health effect type	Specifies whether the health effect is a risk (negative) or benefit (positive).
Risk metric type	Report risks in terms of hazard index (HI = 1/MOE) or margin of exposure.
Left margin safety plot	Left margin of the plot for margins of exposure or hazard indices.
Right margin safety plot	Right margin of the plot for margins of exposure of hazard indices.
Show equivalent animal dose output	Specifies whether equivalent animal doses should be reported in the output.
Threshold safety plot	Threshold for interpretation in the margin of exposure or hazard index plot, e.g. MOE = HI = 1 or MOE = 100.
Inclusion percentage variability interval	The central percentage of the variability distribution to include in intervals for exposure, hazard and MOE (e.g. 90 means p5-p95).
Number of plot labels	Maximum number of labels to plot in hazard vs exposure plot.
Number of substances	Maximum number of substances to plot in hazard vs exposure plot.
Use inverse distribution to calculate percentile	Calculate percentile via the complementary percentage of the inverse distribution (default: no). Description: E.g., P0.1 of MOE distribution is calculated via P99.9 of 1/MOE distribution. Note: This option is provided because percentile calculation in small data sets is asymmetric in both tails.