Hazard characterisations

Hazard characterisations are benchmark doses for active substances and for the chosen effect at the chosen target level (external or internal) of the hazard assessment. Hazard characterisations are based on points of departure, such as BMDs from dose-reponse models or externally specified points of departure (MDSs, NOAELs or LOAELs). The computation may involve inter-species conversion, intra-species factors and the use of kinetic models or absorption factors to convert external doses to internal doses.

This module has as primary entities: Substances Effects

Output of this module is used by: Relative potency factors Risks

Calculation of hazard characterisations

Inputs used: Active substances Dose response models Effect representations Points of departure Inter-species conversions Intra species factors Kinetic models

Settings used

Settings and Tiers