Relative potency factors data formats

Relative potency factors

Relative potency factors quantify relative potencies of substances with respect to an effect and can be used to express combined exposures of multiple substances in terms of the exposure value of the chosen index substance (i.e., as index substance equivalents). Relative potency factors can be provided in case hazard characterisations are missing. If available, the uncertainty of externally specified RPFs can be specified with uncertainty sets (empirical distributions representing possible values) in an additional table.

Relative potency factors

Relative potency factors are linked to an effect using the effect code (idEffect) and to substances using the substance code (idSubstance).

Table aliases: RelativePotencyFactors, RelativePotencyFactor, RawRelativePotencyFactors.

Table 152 Table definition for RelativePotencyFactors.

Name	Type	Description	Aliases	Required
idSubstance	AlphaNumeric(50)	The code of the substance.	idSubstance, SubstanceId, SubstanceCode, Substance, idCompound, CompoundId, CompoundCode, Compound	Yes
idEffect	AlphaNumeric(50)	The effect code.	idEffect, EffectId, Effect	Yes
RPF	Numeric	The relative potency factor.	RPF, RelativePotencyFactor	Yes

Relative potency factor uncertainty

This table contains sets of values representing the uncertainty for relative potency factors.

Table aliases: RelativePotencyFactorsUncertain, RelativePotencyFactorUncertain, RawRelativePotencyFactorsUncertain.

Table 153 Table definition for RelativePotencyFactorsUncertain.

Name	Type	Description	Aliases	Required
idUncertaintySet	AlphaNumeric(50)	The uncertainty set identification number. During each uncertainty iteration one set is used.	idUncertaintySet, UncertaintyId	Yes
idEffect	AlphaNumeric(50)	The effect code (must correspond to values in id column of Effects table).	idEffect, EffectId, Effect	Yes
idSubstance	AlphaNumeric(50)	The substance code (must correspond to values in id column of Substances table).	idSubstance, SubstanceId, SubstanceCode, Substance, idCompound, CompoundId, CompoundCode, Compound	Yes
RPF	Numeric	The relative potency factor.	RPF, RelativePotencyFactor	Yes