Risks settings

Calculation settings

Table 197 Calculation settings for module Risks.
Name Description

Multiple substances analysis

Specifies whether the assessment involves multiple substances.

Express results in terms of reference substance equivalents (cumulative)

Specifies whether the assessment involves multiple substances and results should be cumulated over all substances.

Health effect type

Specifies whether the health effect is a risk (negative) or benefit (positive).

Risk metric type

Report risks in terms of hazard index (HI = 1/MOE) or margin of exposure.

Left margin safety plot

Left margin of the plot for margins of exposure or hazard indices.

Right margin safety plot

Right margin of the plot for margins of exposure of hazard indices.

Show equivalent animal dose output

Specifies whether equivalent animal doses should be reported in the output.

Threshold safety plot

Threshold for interpretation in the margin of exposure or hazard index plot, e.g. MOE = HI = 1 or MOE = 100.

Inclusion percentage variability interval

The central percentage of the variability distribution to include in intervals for exposure, hazard and MOE (e.g. 90 means p5-p95).

Number of plot labels

Maximum number of labels to plot in hazard vs exposure plot.

Number of substances

Maximum number of substances to plot in hazard vs exposure plot.

Use inverse distribution to calculate percentile

Calculate percentile via the complementary percentage of the inverse distribution (default: no). Description: E.g., P0.1 of MOE distribution is calculated via P99.9 of 1/MOE distribution. Note: This option is provided because percentile calculation in small data sets is asymmetric in both tails.

Target level

Select to express hazard characterisations at external or internal exposure level.

Risk type

The type of exposure considered in the assessment; acute (short term) or chronic (long-term).