Kinetic models data formats

Data tables:

  • Absorption factors

  • Kinetic model instances

  • Kinetic model instance parameters

Kinetic models

Kinetic models may be specified as kinetic model instances that contain parameter specifications of built in kinetic models or as simple absorption factors.

Kinetic model instances

Kinetic model instances.

Table aliases: KineticModelInstances, KineticModelInstance.

Table 183 Table definition for KineticModelInstances.
Name Type Description Aliases Required

idModelInstance

AlphaNumeric(50)

Unique identification code of the kinetic model instance.

idModelInstance, Id, Code

Yes

idModelDefinition

KineticModelType

Identifier of the kinetic model definition for which this is an instance.

idModelDefinition, ModelDefinition

Yes

idTestSystem

AlphaNumeric(200)

The species on which the experiment was performed.

System, TestSystem

Yes

idSubstance

AlphaNumeric(50)

Unique identification code of substance, Default: valid for all substances. Should be omitted for parameters in the class Physiological

idSubstance, SubstanceId, SubstanceCode, Substance

No

Reference

AlphaNumeric(100)

Reference or author.

References

No

Kinetic model instance parameters

Kinetic model parameters

Table aliases: KineticModelInstanceParameters, KineticModelInstanceParameter.

Table 184 Table definition for KineticModelInstanceParameters.
Name Type Description Aliases Required

idModelInstance

AlphaNumeric(50)

Unique identification code of the kinetic model instance to which this parameter belongs

Id, Code

Yes

Parameter

AlphaNumeric(100)

Name of the parameter in the kinetic model.

Yes

Description

AlphaNumeric

Description of or reference for the parameter values in the kinetic model.

No

Value

Numeric

Mean.

MEAN, mean

Yes

DistributionType

AlphaNumeric(20)

Distribution.

DistributionType, Distribution

No

CvVariability

Numeric

Variability.

No

CvUncertainty

Numeric

Uncertainty.

No

Kinetic model absorption factors

Kinetic absorption factors

Table aliases: KineticAbsorptionFactors, KineticAbsorptionFactor, AbsorptionFactors, AbsorptionFactor.

Table 185 Table definition for KineticAbsorptionFactors.
Name Type Description Aliases Required

idCompound

AlphaNumeric(50)

code of substance (must correspond to values in id column of Substances table)

idSubstance, SubstanceId, SubstanceCode, Substance

No

Route

AlphaNumeric(50)

Non-dietary route or pathway, use ‘Oral’, ‘Dermal’, or ‘Inhalation’ to specify the route.

Route, Pathway

No

AbsorptionFactor

Numeric

absorption factor value

AbsorptionFactor, Factor

No