Dietary exposures tiers

Overview

Table 83 Tier overview for module Dietary exposures.
Name EFSA 2012 Optimistic EFSA 2012 Pessimistic - Acute EFSA 2012 Pessimistic - Chronic EC 2018 Tier 1 EC 2018 Tier 2

Risk type

Acute

Chronic

Compute exposures based on total diet study data

false

false

false

false

Dietary intake calculation method

DistributionEstimates

DistributionEstimates

DistributionEstimates

DistributionEstimates

DistributionEstimates

Refined method choice

false

false

false

false

false

Sample based

true

true

true

true

true

Consumptions on the same day come from the same sample

false

true

true

false

false

Processing factor model

Fixed

FixedAllowHigher

FixedAllowHigher

Fixed

Fixed

Unit variability model

NoUnitVariability

BetaDistribution

BetaDistribution

BetaDistribution

Estimates nature

Realistic

Realistic

Realistic

Unit variability parameter

VariabilityFactor

VariabilityFactor

VariabilityFactor

Model type

OIM

OIM

OIM

OIM

Model-then-add

false

false

false

false

Covariate modelling

false

false

false

false

false

Iterate survey

false

false

false

false

false

Report consumptions and exposures per individual instead of per kg body weight

false

false

false

false

false

EFSA 2012 Optimistic

Use the optimistic model settings according to the EFSA Guidance 2012. Concentration values are sampled using a sample-based empirical distribution. Available processing factors are applied. No unit vatiability model should be applied.

Table 84 Tier definition for EFSA 2012 Optimistic.
Name Setting

Compute exposures based on total diet study data

false

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

false

Processing factor model

Fixed

Unit variability model

NoUnitVariability

Model type

OIM

Model-then-add

false

Covariate modelling

false

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 85 Input tiers for EFSA 2012 Optimistic.
Module Input tier
Concentration models EFSA 2012 Optimistic

EFSA 2012 Pessimistic - Acute

Acute probabilistic exposure assessment using the pessimistic model settings according to the EFSA Guidance 2012. Only processing factors > 1 are applied. For unit variability, the Beta distribution is applied.

Table 86 Tier definition for EFSA 2012 Pessimistic - Acute.
Name Setting

Risk type

Acute

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

true

Processing factor model

FixedAllowHigher

Unit variability model

BetaDistribution

Estimates nature

Realistic

Unit variability parameter

VariabilityFactor

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 87 Input tiers for EFSA 2012 Pessimistic - Acute.
Module Input tier
Concentration models EFSA 2012 Pessimistic - Acute

EFSA 2012 Pessimistic - Chronic

Chronic probabilistic exposure assessment using the pessimistic model settings according to the EFSA Guidance 2012. Only processing factors > 1 are applied.

Table 88 Tier definition for EFSA 2012 Pessimistic - Chronic.
Name Setting

Risk type

Chronic

Compute exposures based on total diet study data

false

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

true

Processing factor model

FixedAllowHigher

Model type

OIM

Model-then-add

false

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 89 Input tiers for EFSA 2012 Pessimistic - Chronic.
Module Input tier
Concentration models EFSA 2012 Pessimistic - Chronic

EC 2018 Tier 1

Table 90 Tier definition for EC 2018 Tier 1.
Name Setting

Compute exposures based on total diet study data

false

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

false

Processing factor model

Fixed

Unit variability model

BetaDistribution

Estimates nature

Realistic

Unit variability parameter

VariabilityFactor

Model type

OIM

Model-then-add

false

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 91 Input tiers for EC 2018 Tier 1.
Module Input tier
Concentration models EC 2018 Tier 1

EC 2018 Tier 2

Table 92 Tier definition for EC 2018 Tier 2.
Name Setting

Compute exposures based on total diet study data

false

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

false

Processing factor model

Fixed

Unit variability model

BetaDistribution

Estimates nature

Realistic

Unit variability parameter

VariabilityFactor

Model type

OIM

Model-then-add

false

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 93 Input tiers for EC 2018 Tier 2.
Module Input tier
Concentration models EC 2018 Tier 2

EFSA 2012 Pessimistic

Note

This tier is deprecated and has been replaced by separate acute/chronic tiers.

Probabilistic exposure assessment using the pessimistic model settings according to the EFSA Guidance 2012. Only processing factors > 1 are applied. For unit variability, the Beta distribution is applied.

Table 94 Tier definition for EFSA 2012 Pessimistic.
Name Setting

Compute exposures based on total diet study data

false

Dietary intake calculation method

DistributionEstimates

Refined method choice

false

Sample based

true

Consumptions on the same day come from the same sample

true

Processing factor model

FixedAllowHigher

Unit variability model

BetaDistribution

Estimates nature

Realistic

Unit variability parameter

VariabilityFactor

Model type

OIM

Model-then-add

false

Covariate modelling

false

Iterate survey

false

Report consumptions and exposures per individual instead of per kg body weight

false

Input tiers

Table 95 Input tiers for EFSA 2012 Pessimistic.
Module Input tier
Concentration models EFSA 2012 Pessimistic