Substances
Substances are chemical entities that can refer to: 1) active substances such as investigated in toxicology; 2) measured substances such as defined in specific analytical methods. MCRA assessments can have one or more substances as the scope. When more than one substance is specified, there is an option to perform a cumulative assessment. In that case one of the substances has to be indicated as the index/reference substance, and results will be expressed in equivalents of the index substance.
Output of this module is used by: Dust exposure determinants Soil exposure determinants Air exposure determinants Consumer product exposure determinants Food concentrations Food concentration distributions Dust concentrations Dust concentration distributions Soil concentrations Soil concentration distributions Air concentration distributions Indoor air concentrations Outdoor air concentrations Single value concentrations Processing factors Unit variability factors Occurrence patterns Occurrence frequencies Substance authorisations Substance approvals Substance conversions Deterministic substance conversion factors Concentration limits Food concentration models Modelled foods Focal food concentrations Consumer product concentrations Consumer product concentration distributions Food conversions Consumptions by modelled food High exposure food-substance combinations Dietary exposures Single value dietary exposures Single value non-dietary exposures Non-dietary exposures Internal exposures Exposure mixtures HBM concentrations HBM analysis Exposure comparisons Dust exposures Soil exposures Air exposures Consumer product exposures HBM single value exposures Occupational task exposures Occupational exposures Exposure biomarker conversions QSAR membership models Molecular docking models Absorption factors PBK model parametrisations Kinetic conversion factors Active substances Relative potency factors Hazard characterisations Points of departure Dose response models Dose response data Inter-species conversions Intra species factors Exposure response functions Risks Single value risks Environmental burden of disease