Training prospective risk assessment chronic Tier II

This standard action is of type: Single value risks

This standard action allows you to run and compare the background and different Tier II approaches to probabilistic chronic prospective risk assessment for a newly proposed use (focal substance/food) as defined by the EC working group. This is a chronic risk assessment of an effect (hypothyroidism) for the Dutch toddlers, Dutch other children and German adults populations. The focal food and substance combination that can be selected are cyprodinil with apples (fictitious data), valifenalate with lettuce or valifenalate with aubergines. The focal exposure can be based on a GAP or actual exposure scenario as defined by the working group, or it can be omitted (for comparison) so that only the background exposure is calculated. The 99.9th percentile of the exposure has been adjusted using uncertain adjustment factors from the EFSA cumulative risk assessment report 2020. The exposure is calculated probabilistically and. the risk is expressed as margin of exposure (MOE) and is compared to a threshold value of 100.

Table 249 Datasources for Training prospective risk assessment chronic Tier II.
Table Group Name Repository Type

FocalFoods

FocalConcentrations-ActualScenario.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Variable

FocalFoods

FocalConcentrations-GAPScenario.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

FocalFoods

FocalConcentrations-GapScenario.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Variable

AssessmentGroupMemberships

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

AuthorisedUses

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Compounds

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Effects

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

FoodExtrapolations

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

FoodTranslations

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Foods

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

HazardDoses

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

MaximumResidueLimits

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Variable

Processing

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

ResidueDefinitions

SecondaryInputDataMRL2016.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

MaximumResidueLimits

SecondaryInputDataMRL2019.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Variable

DeterministicSubstanceConversionFactors

SingleValueCalculations.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Concentrations

c_ConcentrationsSSD_TCF.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Survey

c_ConsumptionsDE.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Survey

c_ConsumptionsNL2.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed

Survey

c_ConsumptionsNL3_6.mdb

Standard Actions/Training Chronic Prospective Risk Assessment Tier II

Fixed