Responses data formats

A response is a measurable endpoint on in a test system. E.g., in a rat test system a response may be the percentage of fatty hepatocytes observed after 90 days. Responses are defined in the responses table.

Responses

Each response is identified by a unique code (idResponse) in a code system of choice, a name, and a description. Also, each response should be linked to a test system (idTestSystem) on which the response is measured. Responses can be of various types (ResponseType), e.g., ContinuousMultiplicative (= non-negative real values using a ratio scale), ContinuousAdditive (= real values using an interval scale), Ordinal, Quantal, or Binary. For continuous variables, the response unit (ResponseUnit) is also relevant. Additionally, also a reference to the test method guideline, e.g., standardised assay kit may also be specified (GuidelineMethod).

Table aliases: Responses, Response.

Table 20 Table definition for Responses.
Name Type Description Aliases Required

idResponse

AlphaNumeric(50)

Unique identification code of the response. In the EuroMix data collection, a EuroMix coding system has been set up in which the id of the test system prefixes the id of the response. E.g., ‘HepaRG-PCR-PPARA’, ‘RatWEC-PCR-CYP26a1’ and ‘MouseDevelopmental-FacialPrimordia-malformed-E9’.

idResponse, ResponseId, Response, Id

Yes

CodeSystem

AlphaNumeric(100)

Identifier of the coding system of the response code.

CodeSystem

No

Name

AlphaNumeric(100)

Name of the response.

Name

No

Description

AlphaNumeric(200)

Additional description or label of the response.

Description

No

idTestSystem

AlphaNumeric(50)

Unique identification code of the test system.

idTestSystem, idSystem, SystemId, TestSystem

Yes

GuidelineMethod

AlphaNumeric(200)

Reference to the test method guideline, e.g., standardised assay kit.

GuidelineMethod

No

ResponseType

ResponseTypes

The data type of the response measurements (e.g., continuous multiplicative, ordinal, categorical).

ResponseType

Yes

ResponseUnit

AlphaNumeric(100)

If the response type is Continuous, then this should be the unit of the response, e.g., kg.

ResponseUnit

No