Inter-species conversions data formats

Inter-species conversions

Inter-species conversion models specify how to convert a hazard dose for a given species to a hazard dose for humans.

Inter-species model parameters

Inter-species extrapolation factors are described using a lognormal distribution specified by a geometric mean (GM) and geometric standard deviation (GSD). Inter-species factors are defined for an effect and a species and may optionally be specified specifically for a substance.

Table aliases: InterSpeciesModelParameters, InterSpeciesModelParameter, InterSpeciesFactors, InterSpeciesFactor.

Table 159 Table definition for InterSpeciesModelParameters.
Name Type Description Aliases Required

idEffect

AlphaNumeric(50)

The code of the effect for which this inter-species model is defined.

idEffect, EffectId, Effect

Yes

idSubstance

AlphaNumeric(50)

The code of the substance for which this inter-species model is defined.

idSubstance, SubstanceId, SubstanceCode, Substance

No

Species

AlphaNumeric(50)

Species

Species

Yes

InterSpeciesGeometricMean

Numeric

Interspecies geometric mean.

InterSpeciesGeometricMean, InterSpeciesGM

Yes

InterSpeciesGeometricStandardDeviation

Numeric

Interspecies geometric standard deviation.

InterSpeciesGeometricStandardDeviation, InterSpeciesGSD

Yes

StandardHumanBodyWeight

Numeric

The standard human body weight.

StandardHumanBodyWeight

Yes

HumanBodyWeightUnit

AlphaNumeric(50)

The unit of the human body weight specification (kg is assumed if not defined).

HumanBodyWeightUnit

No

StandardAnimalBodyWeight

Numeric

The standard animal body weight.

StandardAnimalBodyWeight

Yes

AnimalBodyWeightUnit

AlphaNumeric(50)

The unit of the animal body weight specification (kg is assumed if not defined).

AnimalBodyWeightUnit

No