Single value risks tiers
Overview
| Name | EC 2018 Acute - Tier I | EC 2018 Acute - Tier II | EC 2018 Chronic - Tier I | EC 2018 Chronic - Tier II | EFSA 2022 Acute Tier I | EFSA 2022 Acute Tier II | EFSA 2022 Chronic Tier I | EFSA 2022 Chronic Tier II |
|---|---|---|---|---|---|---|---|---|
Single value risk calculation method |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
FromIndividualRisks |
Exposure type |
Acute |
Acute |
Chronic |
Chronic |
Acute |
Acute |
Chronic |
Chronic |
Risk metric type |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
MarginOfExposure |
Percentage for percentile |
0.1 |
0.1 |
0.1 |
0.1 |
0.1 |
0.1 |
0.1 |
0.1 |
Use inverse distribution to calculate percentile |
true |
true |
true |
true |
true |
true |
true |
true |
Multiple substances analysis |
true |
true |
true |
true |
true |
true |
true |
true |
Compute cumulative risks |
true |
true |
true |
true |
true |
true |
true |
true |
Health effect type |
Risk |
Risk |
Risk |
Risk |
Risk |
Risk |
Risk |
Risk |
Threshold safety plot |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
Target level |
External |
External |
External |
External |
External |
External |
External |
External |
Inclusion percentage variability interval |
99.8 |
99.8 |
99.8 |
99.8 |
99.8 |
99.8 |
99.8 |
99.8 |
Total diet study concentration data |
false |
false |
false |
false |
false |
false |
false |
false |
Compute cumulative exposures |
true |
true |
true |
true |
true |
true |
true |
true |
Sample based |
true |
true |
true |
true |
true |
true |
true |
true |
Consumptions on the same day come from the same sample |
false |
false |
false |
false |
false |
false |
false |
false |
Apply processing factors |
true |
true |
true |
true |
true |
true |
true |
true |
Use distribution |
false |
false |
false |
false |
false |
false |
false |
false |
Ignore processing factors less than 1 |
false |
false |
false |
false |
false |
false |
false |
false |
Use unit variability |
true |
true |
true |
true |
true |
true |
true |
true |
Unit variability model |
BetaDistribution |
BetaDistribution |
BetaDistribution |
BetaDistribution |
BetaDistribution |
BetaDistribution |
BetaDistribution |
BetaDistribution |
Estimates nature |
Realistic |
Realistic |
Realistic |
Realistic |
Realistic |
Realistic |
Realistic |
Realistic |
Unit variability parameter |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
VariabilityFactor |
Model type |
OIM |
OIM |
OIM |
OIM |
OIM |
OIM |
OIM |
OIM |
Model-then-add |
false |
false |
false |
false |
false |
false |
false |
false |
Covariate modelling |
false |
false |
false |
false |
false |
false |
false |
false |
Iterate survey |
false |
false |
false |
false |
false |
false |
false |
false |
Report consumptions and exposures per individual instead of per kg body weight |
false |
false |
false |
false |
false |
false |
false |
false |
Default concentration model |
Empirical |
Empirical |
Empirical |
Empirical |
Empirical |
Empirical |
Empirical |
Empirical |
Include MRL fallback model |
false |
false |
false |
false |
false |
false |
false |
false |
Restrict LOR imputation to authorised uses |
false |
false |
false |
false |
false |
false |
false |
false |
Censored values replacement |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
ReplaceByLOR |
Factor f (f x LOR or f x LOD or LOD + f x (LOQ - LOD) |
0.5 |
0.5 |
0.5 |
0.5 |
0.5 |
0.5 |
0.5 |
0.5 |
Impute missing values from available values (if unchecked, missing values are imputed with 0) |
true |
true |
true |
true |
true |
true |
true |
true |
Correlate imputed values with sample potency |
true |
false |
true |
false |
true |
false |
true |
false |
Use occurrence frequencies for imputation |
true |
true |
true |
true |
true |
true |
true |
true |
Parametric uncertainty |
false |
false |
false |
false |
false |
false |
false |
false |
Apply occurrence pattern percentages |
false |
true |
false |
true |
false |
true |
false |
true |
Substance conversion method |
UseMostToxic |
DrawRandom |
UseMostToxic |
DrawRandom |
UseMostToxic |
DrawRandom |
UseMostToxic |
DrawRandom |
Retain all allocated substances after active substance allocation |
true |
true |
true |
true |
true |
true |
true |
true |
Account for substance authorisations in substance conversions |
false |
true |
false |
true |
false |
true |
false |
true |
Fix duplicate substance allocation inconsistencies |
false |
false |
false |
false |
false |
false |
false |
false |
Use extrapolation rules |
true |
true |
true |
true |
false |
false |
false |
false |
Threshold for extrapolation |
10 |
10 |
10 |
10 |
||||
Restrict extrapolations to equal MRLs |
true |
true |
true |
true |
||||
Restrict extrapolations to authorised uses |
true |
true |
true |
true |
||||
Impute water concentrations |
true |
true |
true |
true |
true |
true |
true |
true |
Water concentration value (µg/kg) |
0.1 |
0.05 |
0.1 |
0.05 |
0.1 |
0.05 |
0.1 |
0.05 |
Restrict water imputation to the five most toxic substances |
true |
true |
true |
true |
true |
true |
true |
true |
Restrict water imputation to authorised uses |
false |
false |
false |
false |
false |
false |
false |
false |
Restrict water imputation to approved substances |
false |
false |
false |
false |
true |
true |
true |
true |
Scale up use frequency to 100% |
true |
true |
true |
true |
||||
Restrict use percentage up-scaling to authorised uses |
true |
true |
true |
true |
||||
Use substance conversion rules |
true |
true |
true |
true |
||||
Ignore sampling weights |
true |
true |
true |
true |
||||
Exclude individuals with less than N days |
false |
false |
true |
true |
||||
N (number of days in survey) |
2 |
2 |
2 |
2 |