Relative potency factors data formats

Relative potency factors quantify relative potencies of substances with respect to an effect and can be used to express combined exposures of multiple substances in terms of the exposure value of the chosen index substance (i.e., as index substance equivalents). Relative potency factors can be provided in case hazard characterisations are missing. If available, the uncertainty of externally specified RPFs can be specified with uncertainty sets (empirical distributions representing possible values) in an additional table.

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Relative potency factors

Relative potency factors are linked to an effect using the effect code (idEffect) and to substances using the substance code (idSubstance).

Accepted table names: RelativePotencyFactors, RelativePotencyFactor.

Table 210 Table definition for Relative potency factors.
Name Type Description Aliases Required

idSubstance

AlphaNumeric (50)

The code of the substance.

idSubstance, SubstanceId, SubstanceCode, Substance

Yes

idEffect

AlphaNumeric (50)

The effect code.

idEffect, EffectId, Effect

Yes

RPF

Numeric

The relative potency factor.

RPF, RelativePotencyFactor

Yes

Relative potency factor uncertainty

This table contains sets of values representing the uncertainty for relative potency factors.

Accepted table names: RelativePotencyFactorsUncertain, RelativePotencyFactorUncertain.

Table 211 Table definition for Relative potency factor uncertainty.
Name Type Description Aliases Required

idUncertaintySet

AlphaNumeric (50)

The uncertainty set identification number. During each uncertainty iteration one set is used.

idUncertaintySet, UncertaintyId

Yes

idEffect

AlphaNumeric (50)

The effect code (must correspond to values in id column of Effects table).

idEffect, EffectId, Effect

Yes

idSubstance

AlphaNumeric (50)

The substance code (must correspond to values in id column of Substances table).

idSubstance, SubstanceId, SubstanceCode, Substance

Yes

RPF

Numeric

The relative potency factor.

RPF, RelativePotencyFactor

Yes