Exposures
Exposures are amounts of substances, typically expressed per mass unit and per day, to which individuals in a population are exposed at a chosen target level. This target level may be external exposure (dietary exposure, expressed per unit body weight, or per person) or internal exposure (expressed per unit organ weight). Internal exposures may be aggregated from dietary and non-dietary exposures using either absorption factors or kinetic models to translate the external exposures to internal exposures. Exposures can be short-term/acute exposures and then contain exposures for individual-days, or they can be long-term/chronic exposures, in which case they represent the average exposure per day over an unspecified longer time period.
This module has as primary entities: Populations Foods Substances
Output of this module is used by: Exposure mixtures Biological matrix concentration comparisons Risks
Calculation of exposures
Exposures are computed by linking dietary and (if available) non-dietary individual/individual-day exposures and computing the (aggregated) internal exposures at the specified target compartment.
Inputs used: Dietary exposures Non-dietary exposures Active substances Relative potency factors Kinetic models
Settings used