Points of departure

Externally specified points of departure can be used as an alternative to calculated BMDs from dose response models. Points of departure can be of various types, such as NOAEL, LOAEL or BMD. They can be used to construct the list of active substances, to derive relative potency factors, and to perform health impact assessments.

This module has as primary entities: Substances Effects

Output of this module is used by: Active substances Hazard characterisations

Points of departure as data

Points of departure are provided as data for combinations of substance and effect and each is minimally described by a reference value and a type (e.g., NOAEL or LOAEL). In addition, the exposure route, specifies, and references may be specified.

Inputs used: AOP networks

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