Dose response models settings

Calculation settings

Table 221 Calculation settings for module Dose response models.
Name Type Description
Index substance

AlphaNumeric

The substance of interest or index substance.
Calculate a parametric benchmark dose confidence interval

Boolean

A parametric benchmark dose confidence interval (90%) is calculated by the profile likelihood method. If unchecked, the confidence interval is based on a bootstrap sample with uncertainty bounds p5 and p95.

Uncertainty settings

Table 222 Uncertainty settings for module Dose response models.
Name Type Description
Resample hazard characterisations or RPFs

Boolean

Specifies whether to resample the hazard characterisations or relative potency factors. Requires hazard characterisation or RPF uncertainty to be quantified in DoseResponseModelsUncertain or RelativePotencyFactorsUncertain tables.