Health impact estimates

Introduction

The goal of this exercise is to assess a health impact estimate.

Preparation

If you haven’t done so, in the workspace browser (use the  icon), create a new workspace named Examples, using the .

The data files used in the example(s) in this section, are located in the data folder Documentation-Examples / Exercise Health Impact.

Example 1

• In the Examples workspace, create a new action (using )

  • Then select  Show all action types,select Risks

  • Name it Risks

  • Press Create

• Then go to the Actions settings  of this action (path: Risks)

  • At Scope, click Effects (path: Risks / Effects)

    • At Effects data source with  browse to the file Effects and AOP Network Steatosis.xlsx and Select

    • At * Effect settings*, for focal effect select Steatosis-liver and press  Save Changes

    • In the green navigation bar, click Risks to go up one level

• At Scope, click Foods (path: Risks / Foods)

  • At Foods data source with  browse to the file Foods.xlsx and Select

  • In the green navigation bar, click Risks to go up one level

• At Scope, click Substances (path: Risks / Substances)

  • At Substances data source with  browse to the file Substances.xlsx and Select

  • At Substance settings, for index substance select Cyproconazole, and press  Save Changes

  • In the green navigation bar, click Risks to go up one level

• At Inputs, click Exposures (path: Risks / Exposures)

  • At Inputs, click Dietary exposures (path: Risks /Exposures / Dietary exposures)

    • At Inputs, click Consumptions by food measured (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food)

      • At Inputs, click Consumptions (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food / Consumptions)

        • At Consumptions data source with  browse to the file Consumptions.xlsx and Select

        • At Consumptions data selection with  open the food consumption surveys selection.

          • The file contains two surveys, but only one is allowed. So deselect everything by clicking  on the first line, next to the word Code

          • Now select DNFCS_2003 and press Save (the red warning  should now be gone)

        • At Consumptions settings for Food survey select DNFCS_2003 and press  Save Changes

        • In the green navigation bar, click Consumptions by modelled food to go up one level

      • At Inputs, click Food conversions (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food / Food conversions)

        • At Inputs click Food as modelled (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food / Food conversions / Food as modelled)

          • At Inputs, click Concentrations (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food / Food conversions / Food as modelled / Concentrations)

            • At Concentrations data source with  browse to the file UserGroupDemo-ConcentrationData.xlsx and Select

            • In the green navigation bar, click Food conversions to go up two levels

        • At Inputs, click Food recipes (path: Risks /Exposures / Dietary exposures / Consumptions by modelled food / Food conversions / Food recipes)

          • At Food recipes data source with  browse to the file UserGroupDemo-FoodRecipes.xlsx and Select

          • In the green navigation bar, click Dietary exposures to go up three levels

    • At Inputs, click Processing factors (path: Risks /Exposures / Dietary exposures / Processing factors)

      • At Processing factors data source with  browse to the file UserGroupDemo-ProcessingFactors.xlsx and Select

      • In the green navigation bar, click Risks to go up three levels

• At Inputs, click Hazard chararcterisations (path: Risks / Hazard chararcterisations)

  • At Inputs, click Active substances (path: Risks / Hazard chararcterisations / Active substances)

    • At Inputs, click Points of departure (path: Risks / Hazard chararcterisations / Active substances / Points of departure)

      • At Points of departure data source with  browse to the file UserGroupDemo-HazardDoses.xlsx and Select

      • In the green navigation bar, click Active substances to go up one level

    • At ‘Active substances’ click  Compute