Effects data formats
Effects are primary entities of the data model. Health effects are defined as (critical) changes relative to a treatment or exposure.
Effects
Effects are uniquely identified by a code (idEffect). Optionally, a name and description can be added. Health effects are commonly distinguished in two types, acute and chronic. Further properties may be specified, e.g. in relation to decision schemes such as the use of thresholds of toxicological concern (TTCs).
Table aliases: Effects, Effect, KeyEvents, KeyEvent.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idEffect |
AlphaNumeric(50) |
Unique identification code of the effect. |
idEffect, EffectId, CodeFocalEffect, Id, Code, KeyEvent, idKeyEvent |
Yes |
CodeSystem |
AlphaNumeric(100) |
Identifier of the coding system of the effect code. |
CodeSystem |
No |
Name |
AlphaNumeric(100) |
Name of the effect. |
Name |
No |
Description |
AlphaNumeric(200) |
Additional description or label of the effect. |
Description |
No |
BiologicalOrganisation |
BiologicalOrganisationType | Biological organisation of the effect: Molecular, Cellular, Tissue, Organ, Individual, Population. This is in line with AOP wiki terminology and can be used for grouping. |
BiologicalOrganisation |
No |
KeyEventProcess |
AlphaNumeric(100) |
Description of AOP Key event component process. E.g., receptor signalling. |
Process |
No |
KeyEventObject |
AlphaNumeric(100) |
Description of AOP Key event component object. E.g., PPAR-alpha. |
Object |
No |
KeyEventAction |
AlphaNumeric(100) |
Description of AOP Key event component action. E.g., decreased. |
Action |
No |
KeyEventOrgan |
AlphaNumeric(100) |
Description of AOP Key event organ. E.g., liver. |
Organ |
No |
KeyEventCell |
AlphaNumeric(100) |
Description of AOP Key event organ. E.g., hepatocyte. |
Cell |
No |
AOPwikiKE |
AlphaNumeric(200) |
Key event ID number in AOP wiki https://aopwiki.org/events Several ID possible Some effects might not be in the wiki, and this field will be empty. |
AOPWikiIds, AOPwikiKE |
No |
Reference |
AlphaNumeric(200) |
External reference(s) to sources containing more information about the AOP key event. E.g., the AOP wiki, and the associated AOP wiki Ids. |
References |
No |