Exposure response functions data formats
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Exposure response functions
Accepted table names: ExposureResponseFunctions, ResponseFunctions, ExposureEffectFunctions.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idModel |
AlphaNumeric (50) |
The unique identifier of the exposure response model. |
idModel, Model, ModelId |
Yes |
Name |
AlphaNumeric (100) |
Name of the exposure response model. |
Name |
No |
Description |
AlphaNumeric (200) |
Additional description or label of the exposure response model. |
Description |
No |
idSubstance |
AlphaNumeric (50) |
The substance code. |
idSubstance, Substance, SubstanceId |
Yes |
idEffect |
AlphaNumeric (50) |
Code of the effect linked to this exposure response function. |
idEffect, EffectId, Effect, EffectCode |
Yes |
TargetLevel |
TargetLevelType | The target level. I.e., internal or external. If omitted, external is assumed. |
TargetLevel, LevelTarget |
No |
ExposureRoute |
ExposureRoute | The exposure route(s) (only applicable if exposure level is external) for which this exposure response function is defined. |
ExposureRoute, Route |
No |
Biological matrix |
BiologicalMatrix | The biological matrix (e.g., blood, urine) for which this exposure response function is defined. |
BiologicalMatrix, MatrixSource, SourceMatrix |
No |
DoseUnit |
DoseUnit | The unit of the result of the exposure response function. |
DoseUnit, Unit |
Yes |
ExpressionType |
ExpressionType | The expression type or adjustment method of the unit. This field specifies how the unit (target) is adjusted, e.g. for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’). |
ExpressionType, AdjustmentMethod |
No |
PopulationCharacteristic |
PopulationCharacteristicType | Population characteristic type. |
Characteristic, idCharacteristic, PopulationCharacteristic, IdPopulationCharacteristic |
No |
EffectThresholdLower |
Numeric (50) |
Lower threshold for the effect for the specified population characteristic. |
EffectThresholdLower |
No |
EffectThresholdUpper |
Numeric (50) |
Upper threshold for the effect for the specified population characteristic. |
EffectThresholdUpper |
No |
Effect metric |
EffectMetric | The type of risk for which this exposure response function is defined. |
EffectMetric, ResponseMetric, Metric |
Yes |
ExposureResponseType |
ExposureResponseType | The type of specification used to define the relation between the exposure and the exposure response. |
ExposureResponseType, ErType, ErfType |
Yes |
ExposureResponseSpecification |
AlphaNumeric (200) |
The specification for the exposure response. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling or perUnit. |
ExposureResponseSpecification, ErfSpecification, ErSpecification |
Yes |
ExposureResponseSpecificationLower |
AlphaNumeric (200) |
Exposure response lower uncertainty bound. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling, or perUnit. |
ExposureResponseSpecificationLower, ErfLower |
No |
ExposureResponseSpecificationUpper |
AlphaNumeric (200) |
Exposure response upper uncertainty bound. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling, or perUnit. |
ExposureResponseSpecificationUpper, ErfUpper |
No |
CounterfactualValue |
Numeric (50) |
Counterfactual value for the exposure response function. Below this exposure the exposure response is evaluated as 1. |
CounterfactualValue, Baseline |
Yes |
CFVUncertaintyDistribution |
CounterFactualValueDistributionType | Distribution type (Uniform, or LogNormal). If not specified, the counter factual value is assumed to be a constant factor. |
CFVUncertaintyDistribution, CFVDistribution |
No |
CFVUpper |
Numeric |
The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is lognormal, then the upper value is assumed to correspond with the p95 percentile of the distribution. For the uniform and lognormal distribution, this value should be greater than the counter factual value. |
CFVUpper, CFVUncertaintyUpper |
No |
Exposure response function subgroups
Exposure response functions defined per exposure category.
Accepted table names: ErfSubgroups, ErfSubgroup.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idModel |
AlphaNumeric (50) |
The unique identifier of the exposure response model. |
idModel |
Yes |
idSubgroup |
AlphaNumeric (50) |
The unique identifier of the subgroup. |
idSubgroup |
Yes |
ExposureUpper |
Numeric (50) |
Specifies the upper bound of the exposure percentile of the exposure response function subgroup. Exposure belong to a subgroup when the exposure is equal or lower than the specified upper bound and larger than the specified upper bound of the previous subgroup. |
ExposureUpper, UpperExposure |
No |
ExposureResponseSpecification |
AlphaNumeric (200) |
The specification for the exposure response. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling, or perUnit. |
ErfSpecification, ExposureResponseSpecification, ExposureResponseFunctionSpecification |
Yes |
ExposureResponseSpecificationLower |
AlphaNumeric (200) |
Exposure response lower uncertainty bound. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling, or perUnit. |
ExposureResponseSpecificationLower, ErfLower |
No |
ExposureResponseSpecificationUpper |
AlphaNumeric (200) |
Exposure response upper uncertainty bound. Either a mathematical expression when the exposure response type is function, or a single value if the exposure response type is constant, perDoubling, or perUnit. |
ExposureResponseSpecificationUpper, ErfUpper |
No |