Exposure biomarker conversions data formats
Describes the exposure biomarker conversions (i.c. conversions within a biological matrix).
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Exposure biomarker conversions
Exposure biomarker conversions main table. Biomarker conversion is within a biological matrix.
Accepted table names: ExposureBiomarkerConversions, ExposureBiomarkerConversion, BiomarkerConversions, BiomarkerConversion.
| Name | Type | Description | Aliases | Required |
|---|---|---|---|---|
idSubstanceFrom |
AlphaNumeric (50) |
Identification code of substance of the ‘from’ substance. That is, the code of the (measured) substance for which concentrations need to be translated. |
idSubstanceFrom, SubstanceIdFrom, SubstanceCodeFrom, SubstanceFrom |
Yes |
Biological matrix |
BiologicalMatrix | The biological matrix (e.g., blood, urine) for which this conversion rule is defined. |
BiologicalMatrix, MatrixSource, SourceMatrix |
Yes |
ExpressionTypeFrom |
ExpressionType | The expression type (or adjustment method) of the ‘from’-part. This field specifies how the dose unit (source) is expressed, e.g., for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’). |
ExpressionTypeFrom, AdjustmentMethodFrom |
No |
UnitFrom |
DoseUnit | The unit of the ‘from’-part of the conversion rule. |
UnitSourceFrom, SourceUnitFrom |
Yes |
idSubstanceTo |
AlphaNumeric (50) |
Identification code of substance of the ‘to’ substance. |
idSubstanceTo, SubstanceIdTo, SubstanceCodeTo, SubstanceTo |
Yes |
ExpressionTypeTo |
ExpressionType | The expression type or adjustment method of ‘to’-part of the conversion rule. This field specifies how the dose unit (target) is adjusted, e.g., for blood lipids for fat soluble biomarkers (‘mg/g lipids’) or the dilution level of the urine (‘mg/g creatinine’). |
ExpressionTypeTo, AdjustmentMethodTo |
No |
UnitTo |
DoseUnit | The unit of the ‘to’-part of the conversion rule. |
UnitSourceTo, SourceUnitTo |
Yes |
ConversionFactor |
Numeric |
The conversion factor value. If the conversion is provided as a distribution, then this factor is the nominal value of the distribution. |
ConversionFactor, Factor |
Yes |
VariabilityDistributionType |
BiomarkerConversionDistribution | Distribution type (Uniform or LogNormal). If not specified, the conversion is assumed to be a constant factor. |
VariabilityDistributionType, VariabilityDistribution, DistributionType, Distribution |
No |
VariabilityUpper |
Numeric |
The upper value of the distribution. If the distribution is uniform, then it is the upper bound of the uniform distribution. If the distribution is log-normal, then the upper value is assumed to correspond with the p95 percentile of the distribution. When a distribution is assumed, this value should be greater than the conversion factor. |
VariabilityUpper, Upper |
No |